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RESEARCH ARTICLE

Medullary Thyroid Carcinoma Metastatic to the Skin: A Cutaneous Manifestation of a Widely Disseminated Malignancy

The Open Dermatology Journal 29 Apr 2008 RESEARCH ARTICLE DOI: 10.2174/1874372200802010048

Abstract

Metastases located in the skin from thyroid carcinoma, especially the medullary type, are rare and known to occur in the setting of disseminated neoplastic disease.

We report a case of a 72-year-old man, diagnosed as having medullary thyroid carcinoma, on whom a total thyroidectomy and removal of cervical lymph nodes were carried out. The medical treatment after surgery was 131I and hormone therapy. Later, the patient received 60Co teletherapy on the cervical region. On posterior examination, the patient showed a relapse of nodal metastases and pulmonary, hepatic and bone metastases. At that stage, he showed a single nodular lesion on the supraclavicular region. Therefore, a diagnosis of metastatic medullary thyroid carcinoma was made. He had received palliative treatment for the remaining metastatic lesions. During the follow-up, the patient's general condition slowly deteriorated and he died a few days after the last diagnosis. No autopsy was performed.

Keywords: Medullary thyroid carcinoma, skin mestastases, octreotide.
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