A Case of Beau’s Lines at Even Intervals and Onycholysis Caused by Chemotherapy
Tatsuhiko Morioka , Ichiro Kurokawa *, Kei-ichi Yamanaka, Hitomi Sugisaki, Koji Habe, Ken-ichi Isoda, Hitoshi Mizutani
Identifiers and Pagination:Year: 2009
First Page: 16
Last Page: 17
Publisher Id: TODJ-3-16
Article History:Received Date: 26/12/2008
Revision Received Date: 09/01/2009
Acceptance Date: 13/01/2009
Electronic publication date: 30/1/2009
Collection year: 2009
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
We report a case of Beau’s lines at even intervals and onycholysis caused by chemotherapy. The patient with a diffuse large cell B cell lymphoma (DLBCL) stageIIA underwent combination chemotherapy consisting of R-CHOP (Rituximab, cyclophosphamide, doxorubin, vincristine, predonisolone) every three weeks (21-day intervals) six times. As he was treated with R-CHOP, he noticed each Beau’s lines (transverse groove) on all 20 nails each time. In addition, he had onycholysis caused by cyclophosphamide and doxorubicin treatment. Two months after discontinuation of chemotherapy, Beau’s lines disappeared.