RESEARCH ARTICLE
Efficacy of Pimecrolimus in Fox-Fordyce Disease
Arani Chandrakumar1, Nick Francis2, Nilesh Morar*, 1
Article Information
Identifiers and Pagination:
Year: 2010Volume: 4
First Page: 59
Last Page: 61
Publisher ID: TODJ-4-59
DOI: 10.2174/1874372201004010059
Article History:
Received Date: 31/01/2010Revision Received Date: 14/04/2010
Acceptance Date: 10/05/2010
Electronic publication date: 17/6/2010
Collection year: 2010
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Fox-Fordyce disease (FFD) or 'apocrine miliaria' is a rare benign skin condition characterized by obstruction of the apocrine sweat gland. Treatment is generally unsatisfactory. A 15-year-old girl presented with intensely pruritic lesions on her axillae, chest and groin. Histology from an axillary skin biopsy confirmed FFD. The patient was commenced on pimecrolimus cream twice daily for three months and then once daily for a further three months. After a month she had marked improvement of her symptoms. By three months, the papules had flattened. The lesions remained healed at follow up nine months after completing therapy. Pimecrolimus is a safe and easy to use option and we suggest that it may be considered as first-line therapy for FFD.