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RESEARCH ARTICLE

The Use of Topical Calcineurin Inhibitors in Atopic Dermatitis

The Open Dermatology Journal 18 Apr 2014 RESEARCH ARTICLE DOI: 10.2174/1874372201408010012

Abstract

In recent years, two topical calcineurin inhibitors have emerged as effective alternatives to corticosteroids for the treatment of atopic dermatitis. Decisions regarding first line therapy between pimecrolimus and tacrolimus are often based on anecdotal evidence. Herein, we review the current evidence supporting the use of pimecrolimus and tacrolimus in atopic dermatitis as well as key differences in safety, tolerability, and cost between the drugs.

Keywords: Atopic dermatitis, calcineurin inhibitors, pimecrolimus, tacrolimus.
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