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CASE REPORT

Bimodal Temporal Distribution of Herpes Explains Resistant Cases to Oral Antiviral Agents

The Open Dermatology Journal • 31 Jan 2019 • CASE REPORT • DOI: 10.2174/1874372201913010001

Abstract

Herpes Simplex Virus (HSV) is a double-stranded virus that affects the skin and mucous membranes. There has been a long-standing dogma stating that the virus remains dormant and is reactivated from the dorsal root ganglia. However, more recent studies have established that there is a secondary mode of viral reactivation from the epidermis itself. These two distinct reactivation patterns help explain why prophylactic antivirals do not consistently prevent herpes outbreaks.

Keywords: Herpes, Antiviral agents, HSV, Biomodal temporal, Antiviral agents, Mucous membranes.
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