Abstract

Background:

Vitiligo vulgaris is a disfiguring dermatological disease associated with psychosocial impact and decreased quality of life among its sufferers.

Objective:

To provide an overview of quantitative data on the available literature to evaluate the psychosocial impact of depression among vitiligo vulgaris patients in Saudi Arabia and to assess their quality of life (QoL).

Methods:

We searched MEDLINE (PubMed), ResearchGate, and the Cochrane research database between January 1988 and June 2022 to retrieve all studies that assessed the association between depression and QoL among vitiligo vulgaris patients in Saudi Arabia.

Results:

A total of 11 studies were included—5 studies addressed depression among vitiligo vulgaris patients, and 6 studies addressed QoL. The prevalence of depression among Saudi vitiligo vulgaris patients varies between 37.1% and 54.6%, and the pooled prevalence is 45.81 based on a random effects model. The mean ± standard deviation of the Dermatology Life Quality Index (DLQI) is between 5.64 ± 5.2 and 14.72 ± 5.173. Psychosocial impact is found to be associated with vitiligo vulgaris and an impairment of QoL.

Conclusion:

Depression has common psychosocial symptoms among Saudi vitiligo vulgaris patients and has a negative impact on their QoL.

Keywords: Vitiligo vulgaris, Depression, DLQI, Disfiguring dermatological disease, Depigmentation.
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