SYSTEMATIC REVIEW


Depression and Quality of Life among Saudi Patients with Vitiligo: A Descriptive Quantitative Review



Faisal A. Alzeer1, *
iD
, Abdulmageed Alajlan1
iD
, Sulaiman A. Alshammari2
iD
, Shaik Shaffi Ahamed2
iD
, Abdulaziz H. Alzeer3
iD

1 Department of Dermatology, College of Medicine, King Saud University. Riyadh, Saudi Arabia
2 Department of Family & Community Medicine, College of Medicine, King Saud University. Riyadh, Saudi Arabia
3 Department of Critical Care, College of Medicine, King Saud University, Riyadh, Saudi Arabia


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Creative Commons License
© 2023 Alzeer et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Department of Dermatology, College of Medicine, King Saud University, P.O. Box 18321, Riyadh 11415, Saudi Arabia; Tel: +966555228033; E-mail: faisalalzeerfz@gmail.com


Abstract

Background:

Vitiligo vulgaris is a disfiguring dermatological disease associated with psychosocial impact and decreased quality of life among its sufferers.

Objective:

To provide an overview of quantitative data on the available literature to evaluate the psychosocial impact of depression among vitiligo vulgaris patients in Saudi Arabia and to assess their quality of life (QoL).

Methods:

We searched MEDLINE (PubMed), ResearchGate, and the Cochrane research database between January 1988 and June 2022 to retrieve all studies that assessed the association between depression and QoL among vitiligo vulgaris patients in Saudi Arabia.

Results:

A total of 11 studies were included—5 studies addressed depression among vitiligo vulgaris patients, and 6 studies addressed QoL. The prevalence of depression among Saudi vitiligo vulgaris patients varies between 37.1% and 54.6%, and the pooled prevalence is 45.81 based on a random effects model. The mean ± standard deviation of the Dermatology Life Quality Index (DLQI) is between 5.64 ± 5.2 and 14.72 ± 5.173. Psychosocial impact is found to be associated with vitiligo vulgaris and an impairment of QoL.

Conclusion:

Depression has common psychosocial symptoms among Saudi vitiligo vulgaris patients and has a negative impact on their QoL.

Keywords: Vitiligo vulgaris, Depression, DLQI, Disfiguring dermatological disease, Depigmentation.