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A Case of Beau’s Lines at Even Intervals and Onycholysis Caused by Chemotherapy
Tatsuhiko Morioka
Ichiro Kurokawa , *
Kei-ichi Yamanaka
Hitomi Sugisaki
Koji Habe
Ken-ichi Isoda
Hitoshi Mizutani
Authors Info & Affiliations
Kei-ichi Yamanaka
Hitomi Sugisaki
Koji Habe
Ken-ichi Isoda
Hitoshi Mizutani
Authors Info & Affiliations
Abstract
We report a case of Beau’s lines at even intervals and onycholysis caused by chemotherapy. The patient with a diffuse large cell B cell lymphoma (DLBCL) stageIIA underwent combination chemotherapy consisting of R-CHOP (Rituximab, cyclophosphamide, doxorubin, vincristine, predonisolone) every three weeks (21-day intervals) six times. As he was treated with R-CHOP, he noticed each Beau’s lines (transverse groove) on all 20 nails each time. In addition, he had onycholysis caused by cyclophosphamide and doxorubicin treatment. Two months after discontinuation of chemotherapy, Beau’s lines disappeared.
