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Molecular Cryo-Electron Tomography of Skin
Abstract
The three-dimensional structure of skin can be studied at near-native conditions at the molecular level with a new technique called molecular electron tomography of vitreous tissue sections (tissue TOVIS). Its usage is, however, still largely limited by a difficult sample handling procedure. Here we discuss some measures for the efficient application of tissue TOVIS to dermatological research.
Keywords: Skin barrier, cryo-electron microscopy of vitreous sections, CEMOVIS, cryo-electron tomography of vitreous sections, TOVIS.
