RESEARCH ARTICLE


Main Allergens Observed in Patients with Contact Dermatitis in a Brazilian Population Group



Zamir Calamita, Ana Cristina Rizzo Alonso, Lorena Carla Oliveira da Costa, Andrea Bronhara Pelá Calamita
Marília Medical School (FAMEMA), São Paulo, Brazil


Article Metrics

CrossRef Citations:
0
Total Statistics:

Full-Text HTML Views: 774
Abstract HTML Views: 1498
PDF Downloads: 804
Total Views/Downloads: 3076
Unique Statistics:

Full-Text HTML Views: 458
Abstract HTML Views: 941
PDF Downloads: 601
Total Views/Downloads: 2000



Creative Commons License
© Calamita et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Marília Medical School (FAMEMA), Vicente Ferreira, 648, Marília, São Paulo, Brazil; Tel: (55)14-34546548; E-mails: calamita@unimedmarilia.com.br and zcalamita@hotmail.com


Abstract

Background: The skin contact test or patch test is considered to be a fundamental tool for investigating allergic contact dermatitis (ACD). Better knowledge on the prevalence of allergens in the environment is a good strategy for enabling a better approach towards contact dermatitis (CD) cases.

Objective: The objective of the present study was to evaluate the prevalence of the main allergens of ACD in a population group in the interior of the state of São Paulo, Brazil.

Methods: The results from 368 patch tests on adult patients with CD were evaluated through a retrospective study under the supervision of the Discipline of Allergy and Clinical Immunopathology and the Discipline of Dermatology at the Marília Medical School.

Results: Mean age was 41.2 (± 17.2) years, with predomination of women (71.5%). The majority of the patients (91.3%) presented reactivity to at least one substance. Nickel sulfate and the perfume mix stood out as the most allergenic substances.

Conclusion: Among the variety of substances to be tested in an etiological investigation for CD, perfumes and nickel are especially likely to be allergens in this population group.

Keywords: Allergic contact dermatitis, contact dermatitis, fragrance, nickel, perfume, patch test, skin test.